Neuroblastoma, Homer Wright Rosettes are circular groupings of dark tumor cells surrounding pale neurofibrils (small blue cell tumors from neural crest ectoderm). This histologic finding is found in neuroblastoma, medulloblastoma and...

Neuroblastoma, Homer Wright Rosettes are circular groupings of dark tumor cells surrounding pale neurofibrils (small blue cell tumors from neural crest ectoderm). This histologic finding is found in neuroblastoma, medulloblastoma and retinoblastoma.

Characteristics of neuroblastoma include overexpression of the N-myc oncogene, bombesin tumor marker and neurofilament positive histological stains. 

Note: Do not confuse with Perivascular Pseudorosettes/Rosettes found in Ependymomas

Neuroblastoma, Homer Wright Rosettes are circular groupings of dark tumor cells surrounding pale neurofibrils (small blue cell tumors from neural crest ectoderm). This histologic finding is found in neuroblastoma, medulloblastoma and...

Neuroblastoma, Homer Wright Rosettes are circular groupings of dark tumor cells surrounding pale neurofibrils (small blue cell tumors from neural crest ectoderm). This histologic finding is found in neuroblastoma, medulloblastoma and retinoblastoma.

Characteristics of neuroblastoma include overexpression of the N-myc oncogene, bombesin tumor marker and neurofilament positive histological stains. 

Note: Do not confuse with Perivascular Pseudorosettes/Rosettes found in Ependymomas

Notes:

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    psuedorosette in ependymoma - tumour cells surround central lumen/bv homer wright rosette - tumour cells surround...
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    Pathology student
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    Link is to Pathology Student: Making Pathology Easy and Fun
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    Homer Wright rosettes are characteristic in primitive neuroectodermal tumors (PNETs). PNETs are meduloblastomas, Ewing...
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