The website uses cookies. By using this site, you agree to our use of cookies as described in the Privacy Policy.
I Agree

%3Chead%3E%3Cmeta%20http-equiv=%22Content-Type%22%20content=%22text/html%3Bcharset=utf-8%22%3E%3Clink%20id=%22baseCSS%22%20href=%22https://markups.kdanmobile.com/mymarkup/front/the_components/reformat/base__newsprint.css%22%20rel=%22stylesheet%22%20class=%22newsprint%22%20type=%22text/css%22%3E%3Cstyle%20type=%22text/css%22%20id=%22optionsCSS%22%3E%23body%20%7B%20font-family:%20%22PT%20Serif%22%3B%20font-size:%2016px%3B%20line-height:%201.5em%3B%20color:%20%231F0909%3B%20text-align:%20left%3B%20%7D%20%23text%20%7B%20padding-top:%204.5em%3Bpadding-bottom:%209em%3B%7D%20%23background%20%7B%20background-color:%20%23FFFFFF%3B%20%7D%20.setTextColorAsBackgroundColor%20%7B%20background-color:%20%231F0909%3B%20%7D%20.setBackgroundColorAsTextColor%20%7B%20color:%20%23FFFFFF%3B%20%7D%20.setBackgroundColor%20%7B%20background-color:%20%23FFFFFF%3B%20%7D%20.setTextColor%20%7B%20color:%20%231F0909%3B%20%7D%20%23box,%20.setBoxWidth%20%7B%20width:%2036em%3B%20%7D%20a%20%7B%20color:%20%23065588%3B%20%7D%20a:visited%20%7B%20color:%20%231F0909%3B%20%7D%20@media%20print%20%7B%20body.footnote_links__on_print%20a,%20body.footnote_links__on_print%20a:hover%20%7B%20color:%20%231F0909%20!important%3B%20text-decoration:%20none%20!important%3B%20%7D%20%7D%20body.footnote_links__always%20a,%20body.footnote_links__always%20a:hover%20%7B%20color:%20%231F0909%20!important%3B%20text-decoration:%20none%20!important%3B%20%7D%20img%20%7B%20border-color:%20%231F0909%3B%20%7D%20a%20img%20%7B%20border-color:%20%23065588%3B%20%7D%20a:visited%20img%20%7B%20border-color:%20%231F0909%3B%20%7D%20h1%20a,%20h2%20a,%20a%20h1,%20a%20h2%20%7B%20color:%20%231F0909%3B%20%7D%20h1,%20h2,%20h3,%20h4,%20h5,%20h6%20%7B%20font-family:%20%22PT%20Serif%22%3B%20%7D%20pre%20%7B%20background-color:%20%23FFFFFF%3B%20%7D%20pre,%20code%20%7B%20font-family:%20Inconsolata%3B%20%7D%20hr%20%7B%20border-color:%20%231F0909%3B%20%7D%20html.rtl%20%23body%20%23text%20%7B%20text-align:%20right%20!important%3B%20%7D%20h1,%20h2,%20h3,%20h4,%20h5,%20h6%20%7B%20text-align:%20left%3B%20%7D%20html.rtl%20h1,%20html.rtl%20h2,%20html.rtl%20h3,%20html.rtl%20h4,%20html.rtl%20h5,%20html.rtl%20h6%20%7B%20text-align:%20right%20!important%3B%20%7D%20%23text%20div.separatorLine,%20%23text%20section::before%20%7B%20background:%20%20%20%20%20%20-o-linear-gradient(0,%20%23FFFFFF%201%25,%20%231F0909%2050%25,%20%23FFFFFF%2099%25)%3B%20background:%20%20%20%20-moz-linear-gradient(0,%20%23FFFFFF%201%25,%20%231F0909%2050%25,%20%23FFFFFF%2099%25)%3B%20background:%20-webkit-linear-gradient(0,%20%23FFFFFF%201%25,%20%231F0909%2050%25,%20%23FFFFFF%2099%25)%3B%20%7D%20%3C/style%3E%3Clink%20href=%22https://fonts.googleapis.com/css?family=PT%2BSerif:regular,bold,italic%22%20rel=%22stylesheet%22%20type=%22text/css%22%3E%3Clink%20href=%22https://fonts.googleapis.com/css?family=Inconsolata:regular,bold,italic%22%20rel=%22stylesheet%22%20type=%22text/css%22%3E%3Clink%20id=%22customFileCSS%22%20href=%22https://markups.kdanmobile.com/mymarkup/front/the_components/reformat/custom__newsprint.css%22%20rel=%22stylesheet%22%20type=%22text/css%22%3E%3C/head%3E%3Cbody%20id=%22body%22%20class=%22clearlyReady%20footnote_links__on_print%20large_graphics__do_nothing%22%3E%3Cdiv%20id=%22curtains%22%3E%3C/div%3E%3Cdiv%20id=%22bodyContent%22%3E%3Cdiv%20id=%22box%22%3E%3Cdiv%20id=%22box_inner%22%3E%3Cdiv%20id=%22text%22%3E%3Cdiv%20id=%22pages%22%3E%3Cdiv%20class=%22page%22%20id=%22page1%22%3E%3Cdiv%20class=%22page_content%22%3E%3Cdiv%20id=%22articleHeader%22%3E%3Ch1%20id=%22articleHeader__title%22%3EClinical%20manifestations,%20diagnosis,%20and%20management%20of%20diabetic%20infections%20of%20the%20lower%20extremities%3C/h1%3E%3Cdiv%20id=%22articleHeader__separator%22%20class=%22separator%22%3E%3Cdiv%20class=%22separatorLine%20setTextColorAsBackgroundColor%22%3E%3C/div%3E%3C/div%3E%3C/div%3E%0A%0A%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%20%20%20%20%20%20%20%0A%20%20%20%20%20%3Cdiv%20id=%22topic-toolbar%22%3E%3Cdiv%20id=%22topic-tools%22%3E%3Cul%3E%3Cli%20id=%22liOutlineToggle%22%3E%3Ca%20id=%22toggleOutline%22%20target=%22_blank%22%3EView%20Topic%20%3C/a%3E%3C/li%3E%20%20%20%20%20%20%20%20%20%3Cli%20id=%22toolsMenu%22%3E%3Ca%20target=%22_blank%22%3ETools%20%3C/a%3E%3C/li%3E%3C/ul%3E%3C/div%3E%20%20%20%3Cdiv%20id=%22topic-title%22%3EClinical%20manifestations,%20diagnosis,%20and%20management%20of%20diabetic%20infections%20of%20the%20lower%20extremities%3C/div%3E%20%20%3C/div%3E%0A%20%20%20%20%0A%20%20%20%20%0A%20%20%20%20%0A%20%20%20%20%0A%20%20%20%20%20%3Cspan%3EView%20in%20%3Ca%20href=%22https://www.uptodate.com/contents/zh-Hans/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities?search=neuropatia%2Bdiabetica%26amp%3Bsource=topic_page%22%20target=%22_blank%22%3EChinese%3C/a%3E%3C/span%3E%3Cp%20id=%22xhash_H1%22%3EINTRODUCTION%3C/p%3EDiabetic%20foot%20infections%20are%20associated%20with%20substantial%20morbidity%20and%20mortality%20%5B%3Ca%20href=%22https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities/abstract/1%22%20target=%22_blank%22%3E1%3C/a%3E%5D.%20Important%20risk%20factors%20for%20development%20of%20diabetic%20foot%20infections%20include%20neuropathy,%20peripheral%20vascular%20disease,%20and%20poor%20glycemic%20control.%20In%20the%20setting%20of%20sensory%20neuropathy,%20there%20is%20diminished%20perception%20of%20pain%20and%20temperature%3B%20thus,%20many%20patients%20are%20slow%20to%20recognize%20the%20presence%20of%20an%20injury%20to%20their%20feet.%20Autonomic%20neuropathy%20can%20cause%20diminished%20sweat%20secretion%20resulting%20in%20dry,%20cracked%20skin%20that%20facilitates%20the%20entry%20of%20microorganisms%20to%20the%20deeper%20skin%20structures.%20In%20addition,%20motor%20neuropathy%20can%20lead%20to%20foot%20deformities,%20which%20lead%20to%20pressure-induced%20soft%20tissue%20damage.%20Peripheral%20artery%20disease%20can%20impair%20blood%20flow%20necessary%20for%20healing%20of%20ulcers%20and%20infections.%20Hyperglycemia%20impairs%20neutrophil%20function%20and%20reduces%20host%20defenses.%20Trauma%20in%20patients%20with%20one%20or%20more%20of%20these%20risk%20factors%20precipitates%20development%20of%20wounds%20that%20can%20be%20slow%20to%20heal%20and%20predispose%20to%20secondary%20infection.%3Cp%3EThe%20microbiology,%20clinical%20evaluation,%20diagnosis,%20and%20management%20of%20diabetic%20foot%20infections%20will%20be%20reviewed%20here.%20The%20general%20evaluation%20of%20the%20diabetic%20foot%20and%20management%20of%20uninfected%20diabetic%20foot%20lesions%20are%20discussed%20separately.%20(See%20%3Ca%20href=%22https://www.uptodate.com/contents/evaluation-of-the-diabetic-foot?search=neuropatia%2Bdiabetica%26amp%3BtopicRef=7651%26amp%3Bsource=see_link%22%20target=%22_blank%22%3E%22Evaluation%20of%20the%20diabetic%20foot%22%3C/a%3E%20and%20%3Ca%20href=%22https://www.uptodate.com/contents/management-of-diabetic-foot-ulcers?search=neuropatia%2Bdiabetica%26amp%3BtopicRef=7651%26amp%3Bsource=see_link%22%20target=%22_blank%22%3E%22Management%20of%20diabetic%20foot%20ulcers%22%3C/a%3E.)%3C/p%3E%3Cp%20id=%22xhash_H905751%22%3EGUIDELINES%3C/p%3EIn%202012,%20the%20Infectious%20Disease%20Society%20of%20America%20updated%20guidelines%20on%20the%20diagnosis%20and%20management%20of%20diabetic%20foot%20infections,%20which%20were%20originally%20published%20in%202004%20%5B%3Ca%20href=%22https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities/abstract/2%22%20target=%22_blank%22%3E2%3C/a%3E%5D.%20Practical%20guidelines%20are%20also%20published%20regularly%20by%20the%20International%20Working%20Group%20on%20the%20Diabetic%20Foot%20%5B%3Ca%20href=%22https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities/abstract/3%22%20target=%22_blank%22%3E3%3C/a%3E%5D.%20The%20information%20reviewed%20in%20this%20topic%20is%20largely%20consistent%20with%20these%20guidelines.%3Cp%3ELinks%20to%20these%20and%20other%20guidelines%20related%20to%20care%20of%20diabetes%20mellitus%20are%20found%20below.%20(See%20%3Ca%20href=%22https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities?search=neuropatia%2520diabetica%26amp%3BtopicRef=1749%26amp%3Bsource=see_link%23H2213154032%22%20target=%22_blank%22%3E'Society%20guideline%20links'%3C/a%3E%20below.)%3C/p%3E%3Cp%20id=%22xhash_H2%22%3EMICROBIOLOGY%3C/p%3EMost%20diabetic%20foot%20infections%20are%20polymicrobial,%20with%20up%20to%20five%20to%20seven%20different%20specific%20organisms%20often%20involved.%20The%20microbiology%20of%20diabetic%20foot%20wounds%20is%20variable%20depending%20on%20the%20extent%20of%20involvement%20%5B%3Ca%20href=%22https://www.uptodate.com/contents/clinical-manifestations-diagnosis-and-management-of-diabetic-infections-of-the-lower-extremities/abstract/4-8%22%20target=%22_blank%22%3E4-8%3C/a%3E%5D:%3Cbr%3E%3Cbr%3E%3C/div%3E%3C/div%3E%3C/div%3E%3C/div%3E%3C/div%3E%3C/div%3E%3Cdiv%20id=%22background%22%3E%3Cdiv%20id=%22background_shading%22%3E%3C/div%3E%3C/div%3E%3C/div%3E%3Clink%20rel=%22stylesheet%22%20href=%22https://markups.kdanmobile.com/mymarkup/front/the_components/reformat/style.css%22%20type=%22text/css%22%3E%3C/body%3E

Summary | 13 Annotations
neuropatía, enfermedad vascular periférica y control glucémico deficiente
2021/05/04 11:27
neuropatía sensorial
2021/05/04 11:28
neuropatía autonómica
2021/05/04 11:28
neuropatía motora
2021/05/04 11:29
a hiperglucemia afecta la función de neutrófilo y reduce las defensas del huésped
2021/05/04 11:29
as infecciones superficiales de los pies diabéticos
2021/05/04 11:30
incluyendo Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pyogenes,y estafilococos coagulasos-negativos
2021/05/04 11:30
organismos anaeróbicos
2021/05/04 11:31
necrosis
2021/05/04 11:31
resultado de úlceras neuropáticas o isquémicas
2021/05/04 11:33
signos sistémicos
2021/05/04 11:35
1) determinar el alcance y la gravedad de la infección, 2) identificar los factores subyacentes que predisponen y promueven la infección, y 3) evaluar la etiología microbiana.
2021/05/04 11:36
desbridamiento agudo
2021/05/04 11:40