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Calcium channel

A calcium channel is an ion channel which shows selective permeability to calcium ions. It is sometimes synonymous with voltage-gated calcium channel,[1] although there are also ligand-gated calcium channels.[2]

Comparison tables[edit]

The following tables explain gating, gene, location and function of different types of calcium channels, both voltage and ligand-gated.

Voltage-gated[edit]

Type Voltage α1 subunit (gene name) Associated subunits Most often found in L-type calcium channel ("Long-Lasting" AKA "DHP Receptor") HVA (high voltage activated) Cav1.1 (CACNA1S) Cav1.2 (CACNA1C) Cav1.3 (CACNA1D) Cav1.4 (CACNA1F) α2δ, β, γ Skeletal muscle, smooth muscle, bone (osteoblasts), ventricular myocytes** (responsible for prolonged action potential in cardiac cell; also termed DHP receptors), dendrites and dendritic spines of cortical neurons
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smooth muscle
2020/03/21 02:53